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This feels like the inflection pointfrom isolated pharmacology to integrated metabolic design

These advantages may include lower immunogenicity, higher loading capacity, and the potential to be engineered for targeted delivery and controlled release (147)

DV-1.8) for the recording electrode

Although several steps in this proposed general mechanism still need detailed confirmation in ex vivo in vitro and in in vivo models through combined metallomic-metabolomic approaches [211,212] and through a systematic physico-chemical study of the involved molecular systems, the collected information allows us to design experimental approaches aimed at verifying the missing steps of the comprehensive model